A Short Note On Endocrine Disruptor Bisphenol A

Endocrine Disruptor: Bisphenol A Introduction: What is BPA? Endocrine disruptors have the ability to enhance or suppress the functions of hormones by mimicking their shape and binding to the appropriate receptor. They also have the capability to change the structure and activity of the endocrine system, potentially causing various adverse effects to the body. One of the most prevalent and dangerous endocrine disruptors is Bisphenol A, or BPA. Bisphenol A is an organic compound with a structure and function similar to that of the hormone estrogen (Kundakovic and Champagne, 2011). Where can BPA be found? Annually, approximately 2 billion pounds of BPA is manufactured in the United States, making it ubiquitous in our everyday lives. BPA is a major component of polycarbonate plastics and epoxy resins. Polycarbonate is most prevalent in materials used for packaging food and drink, such as â€Å"microwave-safe† tupperware and baby bottles. Resins are used in materials for the protective lining of metal water pipes and food and drink containers, such as cans used for fruit and vegetables. BPA can also be found in dental supplies, medical supplies, and children’s toys. When these everyday items are washed, sterilized, or heated, BPA leaches out of the material and into the food to be consumed. Even small amounts of exposure to BPA have been proven to cause adverse effects in humans and animals (Erler and Novak 2010). What is the mechanism of BPA? BPA can act as an estrogen receptorShow MoreRelatedSip (Cogongrass as Main Component of Biodegradable Plastic)2748 Words   |  11 Pagesbeen described as one of the most hazardous consumer products ever created. Leaches di(2-ethylhexyl) phthalate (DEHP) or butyl benzyl phthalate (BBzP), depending on which is used as the plasticizer or softener (usually DEHP). DEHP and BBzP are endocrine disruptors mimicking the female hormone estrogen; have been strongly linked to asthma and allergic symptoms in children; may cause certain types of cancer; linked to negative effects on the liver, kidney, spleen, bone formation and body weight. In Europe